Tumor marker | RH-34697 | RH-21990 | RH-9777 | RH-10515 | RH-13319 | RH-24678 | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Carcinoma in situ | Invasive area | Carcinoma in situ | Invasive area | Carcinoma in situ | Invasive area | Carcinoma in situ | Invasive area | Carcinoma in situ | Invasive area | Carcinoma in situ | Invasive area | |
ER-α, PR | Neg | Neg | Neg | Neg | Neg | Neg | Neg | Neg | Neg | Neg | Neg | Neg |
p53 | Neg | Neg | Neg | Pos | Neg | Neg | Weak Pos | Weak Pos | Neg | Neg | Pos | Pos |
15-PGDH | Pos | Pos | Pos | Pos | Pos | Pos | Pos | Pos | Pos | Pos | Neg | Neg^{a} |
HMG-CoA reductase | Pos | Pos | Pos | Neg | Neg | Neg | Neg | Neg | Neg | Neg | Neg | Neg |
COX-2 | Pos | Pos | Neg | Neg | Pos | Neg | Pos | Pos | Neg | Neg | Pos | Pos |
Psoriasin | Pos | Pos | Pos and Neg | Pos | Neg | Neg | Pos | Pos | Pos | Pos | Pos | Pos |
↵ ^{a} Lack of expression of 15-PGDH by tumor RH-24678 was confirmed by 2D PAGE (see Fig. 15D).