Table III

Functions and gene ontology of potential UBX protein partners (www.flybase.org)

Some proteins have many functions and are thus listed multiple times. The functions of proteins not included in this table are unknown. EF2B, elongation factor 2B; RPL22, ribosomal protein L22; RPN6, protease p44.5 subunit; RPS13, ribosomal protein S13; TRN, tartan; ZF30C, zinc finger protein 30C; Pol, polymerase; TGF, transforming growth factor.

Functional classSpecific functionGene ontology no.
Transcription regulation
    14-3-3εTranscription regulator0030528
    ALRNA Pol II transcription factor0003704
    ALYTranscription co-activator0006352
    APTTranscription regulator0003702
    ARMTranscription co-activator0003713
    CYCKTranscription regulator0030528
    HairyTranscription repressor0016565
    DMI-2Transcription repressor0016564
    NOCTranscription regulator0003702
    SMOXTranscription regulator0030528
    TFIIEβGeneral RNA Pol II transcription factor0016251
    ZF30CTranscription factor0003700
DNA binding
    DIP1aChromatin binding0003682
    DMI-2DNA helicase0004003
    RAD23Damaged DNA binding0003684
Signal transduction
    14-3-3εProtein kinase C inhibitor0004863
    ARMWNT receptor binding0016055
    CYCKProtein kinase activator0019209
    DSHNotch and WNT signaling0005112
    NMOSerine/threonine kinase0004674
    SMOXTGF-β cytoplasmic mediator0005072
Nucleotide phosphatases
    HSC70-4ATPase0016887
    MI-2ATPase0016887
RNA binding/processing
    ALYRNA-binding protein0003723
    APTRNA binding0003723
    CBP80pre-mRNA splicing factor0008248
    DIP1adsRNA binding0003725
    ZN72DRNA binding0003723
Nucleic acid binding
    RPL22Nucleic acid binding0003676
    RPS13Nucleic acid binding0003676
Translation
    EF2BTranslation elongationfactor0003746
    RPL22Ribosome component0003735
    RPS13Ribosome component0003735
Chaperone
    ALYChaperone activity0003754
    HSC70-4Chaperone activity0003754
Other
    ARMCytoskeleton component0005200
    RPN6Endopeptidase0004175
    TRNStructural molecule0005198
  • a Previously identified UBX-interacting protein (24).