Table II

Summary of the 25-plex SH2-microsphere designs

Gene symbolGene nameNCBI accession no.Bead region
PIK3R1-D1Phosphoinositide 3-kinase, regulatory subunit 1 (p85 α) NM_181504 10
PIK3R1-D2Phosphoinositide 3-kinase, regulatory subunit 1 (p85 α) NM_181504 11
CSKc-src tyrosine kinase NM_004383 12
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) NM_005417 21
FGRGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog NM_005248 22
ABL1v-abl Abelson murine leukemia viral oncogene homolog 1 NM_007313 23
RASA1-D1RAS p21 protein activator (GTPase-activating protein) 1 NM_022650 28
RASA1-D2RAS p21 protein activator (GTPase-activating protein) 1 NM_022650 24
YES1v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 NM_005433 25
LCKLymphocyte-specific protein-tyrosine kinase NM_005356 26
PIK3R3-D1Phosphoinositide 3-kinase, regulatory subunit 3 (p55 γ) NM_003629 27
GRAPGRB2-related adaptor protein NM_006613 29
FESFeline sarcoma oncogene NM_002005 30
PIK3R2-D1Phosphoinositide 3-kinase, regulatory subunit 2 (p85 β) NM_005027 81
PIK3R2-D2Phosphoinositide 3-kinase, regulatory subunit 2 (p85 β) NM_005027 82
FYNFYN oncogene related to SRC, FGR, YES NM_002037 83
Grb2Growth factor receptor-bound protein 2 NM_025199 84
PTPN11-D1Protein-tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) NM_018508 85
PTPN11-D2Protein-tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1) NM_018508 86
SHC1SHC (Src homology 2 domain-containing)-transforming protein 1 NM_183001 87
MATKMegakaryocyte-associated tyrosine kinase NM_139355 95
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like NM_005207 96
STAP2Signal-transducing adaptor protein-2 NM_017720 97
BRDG1BCR downstream signaling 1 (BRDG1) NM_012108 98
BTKBruton agammaglobulinemia tyrosine kinase NM_000061 99