Table I

Cellular proteins bound to the 3′-NTR RNA transcript

RNAP, RNA polymerase; HCC, hepatocellular carcinoma; G3P, glyceraldehyde-3-phosphate; mCBP, murine poly(C)-binding protein; snRNA, small nuclear RNA. EWS, Ewing sarcoma; DBC, deleted in breast cancer; KOC, KH domain containing protein overexpressed in cancer.

No.Cellular protein identifiedMolecular massAccession no.
kDa
1Similar to hnRNP A112.3 gi-34879290
2RNAP II co-activator p1514.3 gi-1709514
3Unnamed protein15.9 gi-12845960
4U2 snRNA auxiliary factor27.8 gi-5803207
5DNase I28.9 gi-118922
6Ribosomal protein29.9 gi-306553
7hnRNP A/B-related protein29.8 gi-5052976
8DNase I, chain D29.0 gi-229691
9A + U RNA binding factor30.1 gi-2547076
10p37 AUF131.4 gi-433344
11mCBP34.9 gi-495128
12Y-box-binding protein 135.7 gi-112410
13DNA-binding protein35.8 gi-181914
14HuR36.0 gi-38201714
15G3P dehydrogenase36.0 gi-7669492
16Similar to MGC3730936.3 gi-34857163
172610510D13Rik protein37.0 gi-23274114
18hnRNP X37.5 gi-5453854
19hnRNP A138.8 gi-133254
20β-Polymerase38.2 gi-190156
21Elongation factor 1-α39.6 gi-4530096
22α2-HS glycoprotein38.3 gi-27806751
23p40/AUF142.0 gi-2773158
24Nucleolysin TIA142.9 gi-6094480
25TRK-fused gene43.4 gi-21361320
26hnRNP K50.9 gi-473912
27hnRNP G47.4 gi-542850
28Colligin-246.5 gi-2118393
29Unnamed protein50.1 gi-31092
30TAR DNA-binding protein44.7 gi-6678271
31PTB 257.4 gi-10863997
32Splicing factor U2AF53.4 gi-107723
33Splicing factor homolog54.2 gi-543010
34Staufen protein55.2 gi-4572588
35Rod 156.4 gi-4514554
36Pyruvate kinase57.8 gi-125598
37Splicing factor cc1.358.8 gi-4757926
38PTB isoform a59.6 gi-4506243
39hnRNP L60.1 gi4557645
40HCC autoantigen61.8 gi-4883681
41RNA-binding protein KOC63.6 gi-2105469
42p68 RNA helicase (Ddx5)66.8 gi-226021
43M phase phosphoprotein66.7 gi-1770458
44hnRNP Q266.6 gi-15809588
45FBP67.4 gi-1082624
46EWS68.4 gi-4885225
47FUSE-binding protein 268.3 gi-1575607
48Ku7069.8 gi-4503841
49RNA binding motif protein 1469.4 gi-5454064
50Heat shock 70-kDa-like protein 170.6 gi-1346319
51HspA670.8 gi-87626
52Hsp7070.8 gi-5729877
53DEAD box protein 72 (Ddx17)72.3 gi-3122595
54Hsp A572.0 gi-87528
55DEAD box protein 3 (Ddx3)73.2 gi-3023628
56MTHSP7573.7 gi-292059
57PSF76.1 gi-4826998
58hnRNA-binding protein M477.5 gi-479852
59hnRNP U79.6 gi-16041796
60NF9082.7 gi-5006602
61DNA helicase II82.8 gi-10863945
62Lysine hydroxylase84.6 gi-4505889
63hnRNP U88.9 gi-284156
64DEAH box polypeptide (Ddx15)92.7 gi-4557517
65Matrin 394.5 gi-21626466
66E1B-AP595.7 gi-7512403
67RNA polymerase98.6 gi-30387455
68Golgi-associated particle102.4 gi-486784
69p30 DBC102.7 gi-24432106
70Poly(A) polymerase-1113.0 gi-130781
71RNA helicase A (Dhx9)140 gi-3915658