Table I

Oxidative proteins

The quantitation of 17 proteins associated with the cellular oxidant-antioxidant system met the criteria defined under “Experimental Procedures.” The table shows the protein accession number, the name, the number of sample pairs in which the protein was quantified (Quant pairs), the number of significant peptides (Quant no. peptides), the mean iTRAQ ratio with standard deviation, and the p value if predefined criteria for statistical testing were met.

Swiss-Prot accession no.Protein nameQuant pairsQuant no. peptidesMean ratioS.D.p
P04762 Catalase6801.230.420.0000
P07687 Epoxide hydrolase 1 (microsomal epoxide hydrolase)4230.970.100.1944
P48774 Glutathione S-transferase Mu 5 (GST class Mu 5)2171.720.520.0000
O35660 Glutathione S-transferase Mu 6 (GST class Mu 6)4251.200.450.0333
P00502 Glutathione S-transferase Ya-1 (ligandin)6731.340.330.0000
P04905 Glutathione S-transferase Yb-1 (chain 3)4250.790.260.0005
P08010 Glutathione S-transferase Yb-2 (chain 4)5321.370.470.0001
P08009 Glutathione S-transferase Yb-3 (chain 4)6511.110.320.0180
P04904 Glutathione S-transferase Yc-1 (chain 2)6451.330.390.0000
P11247 Myeloperoxidase precursor (MPO)2131.300.32
Q63716 Peroxiredoxin 1 (thioredoxin peroxidase 2)4461.240.310.0000
O08807 Peroxiredoxin 4 (PRX-IV)2121.030.13
Q9R063 Peroxiredoxin 5, mitochondrial precursor (PRX-V)2151.040.05
O08709 Peroxiredoxin 6 (antioxidant protein 2)6591.320.320.0000
P07632 Cu,Zn-Superoxide dismutase4371.340.190.0000
P07895 Mn-Superoxide dismutase, mitochondrial precursor3181.200.390.0461
P50137 Transketolase (TK)5891.500.480.0000