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October 2006

Volume 5Issue 10p1719-2009
Open Access
On the cover, CAX-PAGE/RPLC-MSMS proteomics platform for discovery of protein biomarkers of traumatic brain injury. Applied to naïve and injured tissue from a controlled cortical impact rat model, proteins are resolved by multidimensional separations and quantified by densitometry. Peptide identification and quantitation are then performed and correlated with protein data. A total of 59 differential proteins were identified. Validation of subsequent protein hits was performed and correlated to biological function. For details, see the article by Kobeissy et al., pages 1887–1898....
On the cover, CAX-PAGE/RPLC-MSMS proteomics platform for discovery of protein biomarkers of traumatic brain injury. Applied to naïve and injured tissue from a controlled cortical impact rat model, proteins are resolved by multidimensional separations and quantified by densitometry. Peptide identification and quantitation are then performed and correlated with protein data. A total of 59 differential proteins were identified. Validation of subsequent protein hits was performed and correlated to biological function. For details, see the article by Kobeissy et al., pages 1887–1898.

Editorial

Biomarkers of Disease and Conditions

Proteomics Data Analysis

Methodologies

Meeting Report

Information

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