February 2007
Volume 6Issue 2p181-368
Open Access
On the cover, an artistic rendition of the nuclear pore complex (NPC) in a cross-section
that highlights the filamentous, natively unfolded domains of its nucleoporins (NPC
proteins). Their highly dynamic and unstructured domains are evolving at an accelerated
pace despite their critical function as gatekeepers of nucleo-cytoplasmic transport.
Image credit: Dr. Samir S. Patel. For details, see the report by Denning and Rexach,
pages 272–282....Show more
On the cover, an artistic rendition of the nuclear pore complex (NPC) in a cross-section
that highlights the filamentous, natively unfolded domains of its nucleoporins (NPC
proteins). Their highly dynamic and unstructured domains are evolving at an accelerated
pace despite their critical function as gatekeepers of nucleo-cytoplasmic transport.
Image credit: Dr. Samir S. Patel. For details, see the report by Denning and Rexach,
pages 272–282.