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February 2007

Volume 6Issue 2p181-368
Open Access
On the cover, an artistic rendition of the nuclear pore complex (NPC) in a cross-section that highlights the filamentous, natively unfolded domains of its nucleoporins (NPC proteins). Their highly dynamic and unstructured domains are evolving at an accelerated pace despite their critical function as gatekeepers of nucleo-cytoplasmic transport. Image credit: Dr. Samir S. Patel. For details, see the report by Denning and Rexach, pages 272–282....
On the cover, an artistic rendition of the nuclear pore complex (NPC) in a cross-section that highlights the filamentous, natively unfolded domains of its nucleoporins (NPC proteins). Their highly dynamic and unstructured domains are evolving at an accelerated pace despite their critical function as gatekeepers of nucleo-cytoplasmic transport. Image credit: Dr. Samir S. Patel. For details, see the report by Denning and Rexach, pages 272–282.

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