July 2007
Volume 6Issue 7p1115-1290
Open Access
On the cover, the automated analysis of unsequenced proteins remains hindered by restrictive
or error-prone sequencing techniques. We show that, not unlike the way the assembly
of DNA reads into genomics sequences, unidentified MS/MS spectra can be assembled
into protein contigs to greatly increase the length and quality of the reconstructed
protein sequences, as demonstrated on a sample of western diamondback rattlesnake
venom extract. For details, see article by Bandeira et al., pages 1123–1134....Show more
On the cover, the automated analysis of unsequenced proteins remains hindered by restrictive
or error-prone sequencing techniques. We show that, not unlike the way the assembly
of DNA reads into genomics sequences, unidentified MS/MS spectra can be assembled
into protein contigs to greatly increase the length and quality of the reconstructed
protein sequences, as demonstrated on a sample of western diamondback rattlesnake
venom extract. For details, see article by Bandeira et al., pages 1123–1134.