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July 2007

Volume 6Issue 7p1115-1290
Open Access
On the cover, the automated analysis of unsequenced proteins remains hindered by restrictive or error-prone sequencing techniques. We show that, not unlike the way the assembly of DNA reads into genomics sequences, unidentified MS/MS spectra can be assembled into protein contigs to greatly increase the length and quality of the reconstructed protein sequences, as demonstrated on a sample of western diamondback rattlesnake venom extract. For details, see article by Bandeira et al., pages 1123–1134....
On the cover, the automated analysis of unsequenced proteins remains hindered by restrictive or error-prone sequencing techniques. We show that, not unlike the way the assembly of DNA reads into genomics sequences, unidentified MS/MS spectra can be assembled into protein contigs to greatly increase the length and quality of the reconstructed protein sequences, as demonstrated on a sample of western diamondback rattlesnake venom extract. For details, see article by Bandeira et al., pages 1123–1134.

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