April 2007
Volume 6Issue 4p575-746
Open Access
On the cover, a ribbon diagram showing the structure of the adipocyte fatty acid binding protein (aP2) modeled with
an internal 4-HNE adjacent to the reactive cysteine (117). Right image (lower) shows the MS/MS sequence data identifying cysteine 117 as the site of covalent modification,
whereas the upper image depicts the feed-forward loop linking oxidative stress to lipid peroxidation and
protein carbonylation. For details, see the article by Grimsrud et al., pages 624–637....Show more
On the cover, a ribbon diagram showing the structure of the adipocyte fatty acid binding protein (aP2) modeled with
an internal 4-HNE adjacent to the reactive cysteine (117). Right image (lower) shows the MS/MS sequence data identifying cysteine 117 as the site of covalent modification,
whereas the upper image depicts the feed-forward loop linking oxidative stress to lipid peroxidation and
protein carbonylation. For details, see the article by Grimsrud et al., pages 624–637.
