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September 2007

Volume 6Issue 9p1459-1669

Open Access

On the cover, the in situ proximity ligation assay offers highly specific detection through the requirement for dual recognition and increased sensitivity via a localized DNA amplification reaction. In this paper we have used secondary proximity probes, suitable to detect proximal binding by pairs of mouse and rabbit antibodies, to visualize phosphorylation of platelet-derived growth factor receptor β in cells and tissues at single molecule resolution. For details, see the article by Jarvius et al., pages 1500–1509....Show more

On the cover, the in situ proximity ligation assay offers highly specific detection through the requirement for dual recognition and increased sensitivity via a localized DNA amplification reaction. In this paper we have used secondary proximity probes, suitable to detect proximal binding by pairs of mouse and rabbit antibodies, to visualize phosphorylation of platelet-derived growth factor receptor β in cells and tissues at single molecule resolution. For details, see the article by Jarvius et al., pages 1500–1509.

September 2007

Editorial Board

Author Index

Research

Salt-induced Changes in the Plasma Membrane Proteome of the Halotolerant Alga Dunaliella salina as Revealed by Blue Native Gel Electrophoresis and Nano-LC-MS/MS Analysis*

Protein Sulfenation as a Redox Sensor

Proteomics Studies Using a Novel Biotinylated Dimedone Analogue *

Glycomics Analysis of Schistosoma mansoni Egg and Cercarial Secretions*

In Situ Detection of Phosphorylated Platelet-derived Growth Factor Receptor β Using a Generalized Proximity Ligation Method*

Mild Performic Acid Oxidation Enhances Chromatographic and Top Down Mass Spectrometric Analyses of Histones*

Consequences of Membrane Protein Overexpression in *Escherichia coli**

Mass Spectrometric Analysis of the Endogenous Type I Interleukin-1 (IL-1) Receptor Signaling Complex Formed after IL-1 Binding Identifies IL-1RAcP, MyD88, and IRAK-4 as the Stable Components*

Quantitative Profile of Five Murine Core Proteomes Using Label-free Functional Proteomics*

Enabling Coupled Quantitative Genomics and Proteomics Analyses from Rat Spinal Cord Samples*

The Implications of Proteolytic Background for Shotgun Proteomics*

Comparative Evaluation of Tandem MS Search Algorithms Using a Target-Decoy Search Strategy*

Shotgun Identification of the Structural Proteome of Shrimp White Spot Syndrome Virus and iTRAQ Differentiation of Envelope and Nucleocapsid Subproteomes *

Technology

Mascot File Parsing and Quantification (MFPaQ), a New Software to Parse, Validate, and Quantify Proteomics Data Generated by ICAT and SILAC Mass Spectrometric Analyses

Application To the Proteomics Study of Membrane Proteins from Primary Human Endothelial Cells *

The Paragon Algorithm, a Next Generation Search Engine That Uses Sequence Temperature Values and Feature Probabilities to Identify Peptides from Tandem Mass Spectra*

Immobilized Zirconium Ion Affinity Chromatography for Specific Enrichment of Phosphopeptides in Phosphoproteome Analysis*

HUPO Views

Human Proteome Organization Proteomics Standards Initiative

Data Standardization, a View on Developments and Policy

Information

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