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September 2014

Volume 13Issue 9p2168-2526
Open Access
On the cover: Illustrates the AlphaScreen nanobead assay, detecting interactions between two proteins. The blue donor bead is excited by a red laser (680 nm) and if the interaction between proteins occurs, the orange acceptor bead luminesces. The method was applied to measure propensity of dimer formation in the human SNX-BAR family. The background shows the color-coded heatmap of interactions obtained. For details, see the article by Emma Sierecki, et al., pages 2233–2245....
On the cover: Illustrates the AlphaScreen nanobead assay, detecting interactions between two proteins. The blue donor bead is excited by a red laser (680 nm) and if the interaction between proteins occurs, the orange acceptor bead luminesces. The method was applied to measure propensity of dimer formation in the human SNX-BAR family. The background shows the color-coded heatmap of interactions obtained. For details, see the article by Emma Sierecki, et al., pages 2233–2245.

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