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December 2014

Volume 13Issue 12p3224-3715
Open Access
On the cover: O-GlcNAc modification of the master osteogenic transcriptional regulator Runx2 [runt-related transcription factor 2/core-binding factor subunit α 1 (Cbfa1)] reveals new links between glucose homeostasis and bone formation. Higher energy collisional dissociation (HCD)-generated HexNAc product ions were utilized to trigger acquisition of electron transfer dissociation (ETD) fragmentation spectra to facilitate characterization of O-GlcNAc modified sites. For details, see the article by Alexis K. Nagel, et al., pages 3381–3395....
On the cover: O-GlcNAc modification of the master osteogenic transcriptional regulator Runx2 [runt-related transcription factor 2/core-binding factor subunit α 1 (Cbfa1)] reveals new links between glucose homeostasis and bone formation. Higher energy collisional dissociation (HCD)-generated HexNAc product ions were utilized to trigger acquisition of electron transfer dissociation (ETD) fragmentation spectra to facilitate characterization of O-GlcNAc modified sites. For details, see the article by Alexis K. Nagel, et al., pages 3381–3395.

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