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May 2023

Volume 22Issue 5

Open Access

Ovarian cancer has a high probability of metastasizing, while exosomes can be seen as a mediator of tumor transmission information. We hope to find exosomes which are key substances for tumor cell transmission information from blood by proteomics. As we can see in the picture, the blue exosomes are conveying various kinds of message including the bio marker LRP1 between blood and tumor tissue. We successfully separated this important substance from huge information....Show more

Ovarian cancer has a high probability of metastasizing, while exosomes can be seen as a mediator of tumor transmission information. We hope to find exosomes which are key substances for tumor cell transmission information from blood by proteomics. As we can see in the picture, the blue exosomes are conveying various kinds of message including the bio marker LRP1 between blood and tumor tissue. We successfully separated this important substance from huge information.

May 2023

Cover

Research Article

Development of a Spectral Library for the Discovery of Altered Genomic Events in Mycobacterium avium Associated With Virulence Using Mass Spectrometry–Based Proteogenomic Analysis

MSFragger-Labile: A Flexible Method to Improve Labile PTM Analysis in Proteomics

Proteomic Analysis of Huntington’s Disease Medium Spiny Neurons Identifies Alterations in Lipid Droplets

Integrative Proteomics and N-Glycoproteomics Analyses of Rheumatoid Arthritis Synovium Reveal Immune-Associated Glycopeptides

N-Terminomic Changes in Neurons During Excitotoxicity Reveal Proteolytic Events Associated With Synaptic Dysfunctions and Potential Targets for Neuroprotection

Quantitative Proteomic Analysis Reveals apoE4-Dependent Phosphorylation of the Actin-Regulating Protein VASP

Translational and Posttranslational Dynamics in a Model Peptidergic System

Technological Innovation and Resources

Bioinertization of NanoLC/MS/MS Systems by Depleting Metal Ions From the Mobile Phases for Phosphoproteomics

Research Article Collection: Cancer Proteomics

Phenotypic Heterogeneity Analysis of APC-Mutant Colon Cancer by Proteomics and Phosphoproteomics Identifies RAI14 as a Key Prognostic Determinant in East Asians and Westerners

Data-Independent Acquisition Phosphoproteomics of Urinary Extracellular Vesicles Enables Renal Cell Carcinoma Grade Differentiation

Deciphering the Clinical Significance and Kinase Functions of GSK3α in Colon Cancer by Proteomics and Phosphoproteomics

Special Issue: Clinical Proteomics

Research

SARS-CoV-2 Variants Show Different Host Cell Proteome Profiles With Delayed Immune Response Activation in Omicron-Infected Cells

Integrated Proteomics to Understand the Role of Neuritin (NRN1) as a Mediator of Cognitive Resilience to Alzheimer’s Disease