Omics
Comparative Secretome Analyses of Primary Murine White and Brown Adipocytes Reveal Novel AdipokinesThe secretome of white and brown primary murine adipocytes, with and without stimulation with norepinephrine (NE), has been determined by using mass spectrometry combined with AHA labeling and pulsed SILAC. The results reported reveal a comprehensive catalogue of novel adipokines secreted from white and brown adipocytes and responsive to NE. Given the beneficial effects of brown fat activation on systemic metabolism and its endocrine function, this study provides an archive of potential brown adipokines and biomarkers for activated brown fat.
Comparative Secretome Analyses of Primary Murine White and Brown Adipocytes Reveal Novel AdipokinesThe secretome of white and brown primary murine adipocytes, with and without stimulation with norepinephrine (NE), has been determined by using mass spectrometry combined with AHA labeling and pulsed SILAC. The results reported reveal a comprehensive catalogue of novel adipokines secreted from white and brown adipocytes and responsive to NE. Given the beneficial effects of brown fat activation on systemic metabolism and its endocrine function, this study provides an archive of potential brown adipokines and biomarkers for activated brown fat.